Dr. Corinna Urmann

Publikationen

Preprint

• Vahekeni, N.; Stehlin, J.; Urmann, C.; Wolfram, E.; Geissmann, Y.; Ruedin, Y.; Engler, O.; Lardos, A. Historical Texts as a Potential Resource for Plant-Derived Natural Products against SARS-CoV-2 – the Example of the Receptarium of Burkhard III von Hallwyl from 16th Century Switzerland. bioRxiv June 13, 2024, p 2024.06.13.598798. https://doi.org/10.1101/2024.06.13.598798

Journal Articles (reviewed)

2024

• Tomou, E.-M.; Goula, K.; Skaltsa, H.; Urmann, C. Comparative Phytochemical Analysis of Cultivated and Wild Sideritis Raeseri Boiss. & Heldr. Subsp. Raeseri Infusions. Natural Product Research 2024. https://doi.org/10.1080/14786419.2024.2309323.
• Jeshua Friedrichs, J.-S.; Schmermund, L.; Urmann, C.; Sieber, V. Synthesis of N-Substituted Pyrrole-2,5-Dicarboxylic Acids from Pyrroles. Helvetica Chimica Acta n/a (n/a), e202400036. https://doi.org/10.1002/hlca.202400036.

2023

• Rothammer, M.; Strobel, P.; Zollfrank, C.; Urmann, C. Biocompatible Coatings Based on Photo-Crosslinkable Cellulose Derivatives. International Journal of Biological Macromolecules 2023, 250, 126063. https://doi.org/10.1016/j.ijbiomac.2023.126063.
• Tomou, E.-M.; Bieler, L.; Spöttl, T.; Couillard-Despres, S.; Skaltsa, H.; Urmann, C. Metabolic Fingerprinting of Different Sideritis Taxa Infusions and Their Neurogenic Activity. Planta Med 2023, 89 (11), 1087–1096. https://doi.org/10.1055/a-2072-2351.
• Urmann, C.; Bieler, L.; Hackl, M.; Chia-Leeson, O.; Couillard-Despres, S.; Riepl, H. Semi-Synthesis of Different Pyranoflavonoid Backbones and the Neurogenic Potential. Molecules 2023, 28 (10), 4023. https://doi.org/10.3390/molecules28104023.

2022

• Baas, J.; Bieringer, S.; Frias, C.; Frias, J.; Soehnchen, C.; Urmann, C.; Ritter, S.; Riepl, H.; Prokop, A. Dihydroxyquingdainone Induces Apoptosis in Leukaemia and Lymphoma Cells via the Mitochondrial Pathway in a Bcl-2- and Caspase-3-Dependent Manner and Overcomes Resistance to Cytostatic Drugs In Vitro. Molecules 2022, 27 (15), 5038. https://doi.org/10.3390/molecules27155038.

2021

• Urmann C., Bieler L., Priglinger E., Couillard-Després S., Aigner L., Riepl H. Neurogenerative Potential of Prenyl– and Pyranocholcones: A Structure-Activity Study, Journal of Natural Products 2021, 84 (10) 2675-2682. DOI:10.1021/acs.jnatprod.1c00505

2020

• Buckett, L.; Schinko, S.; Urmann, C.; Riepl, H.; Rychlik, M. Stable Isotope Dilution Analysis of the Major Prenylated Flavonoids Found in Beer, Hop Tea, and Hops. Front. Nutr. 2020, 7, 619921. https://doi.org/10.3389/fnut.2020.619921.

Before 2020

• Urmann C. and Riepl H.” Semi-Synthetic Approach Leading to 8-Prenylnaringenin and 6-Prenylnaringenin: optimization of the Microwave-Assisted Demethylation of Xantohumol Using Design of Experiments” Molecules 2020, 25(17), 4007, https://doi.org/10.3390/molecules25174007
• Ritter S., Urmann C., Herzog R., Glaser J., Bieringer S., Geisberger T., Wisenreich W. and Riepl H. “Where is Bacosine in Commercially Available Bacopa monnieri?” Planta Medica 2020, 86(8), 565-570. https://doi.org/10.1055/a-1137-4289
• Kirchinger, M*, Bieler L*, Tevini J, Vogl M, Haschke-Becher E, Felder T., Couillard-Despres S, Riepl H and Urmann C (2019). “Development and Characterization of the Neuroregenerative Xanthohumol C/Hydroxypropyl-beta-cyclodextrin Complex Suitable for Parenteral Administration.” Planta Med 85(16): 1233-1241. https://doi.org/10.1055/a-1013-1276 * Authors contribute equally
• Bieler L., Vogl M., Kirchinger M., Urmann C., Riepl H., Bandtlow C., Klimaschewski L., Aigner L., Couillard-Despres S., The Prenylflavonoid ENDF1 Overrules Central Nervous System Growth Inhibitors and Facilitates Regeneration of DRG Neurons, Frontiers in Cellular Neuroscience 2019, 13. https://doi.org/10.3389/fncel.2019.00332
• Venturelli S., Niessner H., Sinnberg T., Berger A., Burkard M., Urmann C., Donaubauer K., Böcker A., Leischner C., Riepl H., Frank J., Lauer U., Garbe C., Busch C. 6- and 8-Prenylnaringenin, Novel Natural Histone Deacetylase Inhibitors Found in Hops, Exert Antitumor Activity on Melanoma Cells. C. Cell Physiol Biochem. 2018;51(2):543-556. https://doi.org/10.1159/000495275.
• Luescher S., Urmann C., Butterweck V. Effects of Hops Derived prenylflavonoids on TNF-α induced barrier dysfunction in intestinal epithelial cells. Journal of Natural Products 2017, 80 (4), pp 925–931; https://doi.org/10.1021/acs.jnatprod.6b00869
• Urmann C., Oberbauer E., Couillard-Despres S.., Aigner L., Riepl H.: Neuro-differentiating Potential of 8‑Prenylnaringenin and Related Compounds in Neural Precursor Cells and Correlation with Estrogen-like Activity. Planta Medica 2015; 81(4):305-311; https://doi.org/10.1055/s-0034-1396243
• Firlbeck, D., Faulstich, M., Urmann, C., Tafesh, A., Azaizeh, H., Riepl, H. Central Composite Design for Optimal Technology of Concentrating Vanillic Acid Using Foam Fractionation. Separation and Purification Technology 2013; 119, 28-34; https://doi.org/10.1016/j.seppur.2013.08.033
• Oberbauer, E.*; Urmann, C.*; Steffenhagen, C.; Bieler, L.; Brunner, D.; Furtner, T.; Humpel, C.; Baeumer, B.; Bandtlow, C.; Couillard-Despres, S.; Rivera, FJ.; Riepl, H.; Aigner, L.; Chroman-like cyclic prenylflavonoids promote neuronal differentiation and neurite outgrowth and are neuroprotective; Journal of Nutritional Biochemistry; 2013, 24(11):1953-62; https://doi.org/10.1016/j.jnutbio.2013.06.005. * Authors contribute equally
• Riepl H., Urmann C. Improved Synthesis of Indirubin Derivatives by Sequential Build-up of the Indoxyl Unit: First Preparation of Fluorescent Indirubins. Helvetica Chimica Acta 2012, 95(8): 1461-1477; https://doi.org/10.1002/hlca.201200042.

Patents

• Riepl H. & Urmann C. Refining process for separation of prenylated polyphenols DE 102012105613 A1
• Aigner L.; Oberbauer-Hofmann, E., Couillard-Despres S., Rivera F., Riepl H., Urmann C., Biendl M.; Chromane-like cyclic prenylflavonoids for the medical intervention in neurological disorders; PCT Int. Appl. (2012) WO 2012172090 A1 20121220

Presentations

• Urmann C., Bieler L., Able T., Huber V., Kirchinger M., Aigner L., Couillard-Despres S. und Riepl H. Natural Products of Hops for Neuroregeneration, Deutscher Fachausschuss Arznei, Gewürz, & Aromapflanzen, Freising September (2023)
• Tomou E., Bieler L., Couillard-Despres S., Skaltsa E. and Urmann C. Neuroregenerative potential of infusions of different Sideritis taxa & metabolic fingerprinting, 70th International Congress and Annual Meeting of the Society-for-Medicinal-Plant-and-Natural-Product-Research, Thessaloniki (2022)
• Urmann C., Kirchinger M., Bieler L. Couillard-Despres S, Riepl H. The Story of Xanthohumol C 69th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, Bonn, online (2021)
• Urmann C. Cyclodextrin-unterstützte Extraktion neurorelevanter Chalkone Jahrestreffen der ProcessNet-Fachgruppe Phytoextrakte 2021 DECHEMA; digital (2021)
• Urmann C. IT TOF supported analysis of natural products, 2019 Shimadzu MS-Tage, Düsseldorf, Germany
• Urmann C, Chia-Leeson O, Märkl S, Stark T, Kirchinger M Inhibition of Histone Deacetylases Using Flavonoids from Hops 2017 International Congress and Annual Meeting of the Society-for-Medicinal-Plant-and-Natural-Product-Research Basel, Switzerland
• Urmann C. Discovery and Development of a Hop-derived Compound for Medicinal Use, 2016, Shimadzu MS-Tage, Berlin, Germany
• Urmann C. Prenylflavonoides—Lead Compounds for Neuro Regeneration 2016 Botanical Center Meeting, University of Illinois in Chicago, Chicago U.S.A
• Urmann C., Riepl H. A new method to enrich differentiation-inducing pyranoflavonoids 2015 International Humulus Symposium, Yakima U.S.A.
• Urmann C., Kirchinger M., Bieler S. Couillard-Despres S., Riepl H. Structural modification of ENDF1 and the effect on inducing differentiation in neural precursor cells, 2015 63th International Congress and Annual Meeting of the Society-for-Medicinal-Plant-and-Natural-Product-Research Budapest, Hungary
• Urmann C., Oberbauer E., Aigner L., Riepl H.: New Differentiation Effect of Hop Prenylflavonoids: Formation of Neurons from Stem Cells; 2013 The XVII International Congress „PHYTOPHARM 2013“; Vienna Austria

Contributions to scientific events (citeable)

• Urmann, C.; Bieler, L.; Hackl, M.; Chia-Leeson, O.; Couillard-Despres, S.; Riepl, H. One-Pot Semi-Synthesis and Neurogenic Potential of Pyranoflavonoids with Different Structural Scaffolds. In Planta Medica; Georg Thieme Verlag KG, 2023; Vol. 89, p P-145. https://doi.org/10.1055/s-0043-1774022.
• Vahekeni, N.; Urmann, C.; Stehlin, J.; Hofer, N.; Gmach, Y.; Wolfram, E.; Lardos, A. Historical Herbal Texts from Switzerland: A Potential Source for Plant- Derived Natural Products against SARS-CoV-2. In Planta Medica; Georg Thieme Verlag KG, 2023; Vol. 89, p P-411. https://doi.org/10.1055/s-0043-1774265.
• Hofer, N.; Urmann, C. Optimization of a GC/MS-Based Screening of Plant Extracts Using GNPS. In Planta Medica; Georg Thieme Verlag KG, 2022; Vol. 88, p P-49. https://doi.org/10.1055/s-0042-1759034.
• Wolf, M.; Emberger-Klein, A.; Werner, K.; Urmann, C.; Riepl, H.; Menrad, K. New Hops-Products for Neuroprotection and Regeneration: Consumer Insights and Product Expectations. In Planta Medica; Georg Thieme Verlag KG, 2022; Vol. 88, p P-321. https://doi.org/10.1055/s-0042-1759291.
• Amm, A.; Egger, A. N.; Menrad, K.; Wolf, M.; Urmann, C.; Emberger-Klein, A. Self-Perceived Knowledge Concerning Herbal Medicine: A Consumer Segmentation Study in Germany. In Planta Medica; Georg Thieme Verlag KG, 2022; Vol. 88, p P-348. https://doi.org/10.1055/s-0042-1759318.
• Tomou, E.-M.; Lytra, K.; Riepl, H.; Skaltsa, H.; Urmann, C. Metabolite Fingerprinting of Sideritis Taxa Infusions. In Planta Medica; Georg Thieme Verlag KG, 2022; Vol. 88, p P-242. https://doi.org/10.1055/s-0042-1759216.
• Able, T.; Urmann, C.; Huber, V.; Riepl, H. Extension of Prenyl Side Chain of Flavanones as Tool to Prevent Cell Death Due to Oxidative Stress. In Planta Medica; Georg Thieme Verlag KG, 2022; Vol. 88, p P-191. https://doi.org/10.1055/s-0042-1759167.
• Riepl, H.; Bieringer, S.; Urmann, C.; Ritter, S.; Baas, J.; Frias, C.; Frias, J.; Soehnchen, C.; Prokop, A. Short Lecture “Rare Isatis Tinctoria Metabolites: Quingdainones Overcome Multidrug Resistance in Leukemia Cells in Vitro.” In Planta Medica; Georg Thieme Verlag KG, 2022; Vol. 88, p SL-D02. https://doi.org/10.1055/s-0042-1758965.
• Urmann, C.; Kirchinger, M.; Bieler, L.; Couillard-Després, S.; Riepl, H. The Story of Xanthohumol C – a Promising Neuro-Regenerative Chalcone from Hops. In Planta Medica; Georg Thieme Verlag, 2021; Vol. 87, p SL25. https://doi.org/10.1055/s-0041-1736773.
• Chia-Leeson O., Riepl H., Urmann C.: Biotransformation of the Promising Neuro-Regenerative Hop-Chalcone Xanthohumol C, 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural 2019: Innsbruck, Austria https://doi.org/10.1055/s-0039-3399972
• Ritter S., Urmann C., Bieler L., Couillard-Després S., Riepl H. Study of Neurodifferentiation Potential of Different Extracts of Bacopa monnieri, 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural 2019: Innsbruck, Austria https://doi.org/10.1055/s-0039-3400091
• Bieringer S., Ritter S., Urmann C., Riepl H.: Isolation of Lyngbyatoxin and other Teleocidin species from ,,Streptomyces Blastmyceticum” Culture. 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural 2019: Innsbruck, Austria, https://doi.org/10.1055/s-0039-3400403
• Urmann C, Chia-Leeson O, Märkl S, Stark T, Kirchinger M Inhibition of Histone Deacetylases Using Flavonoids from Hops 2017 International Congress and Annual Meeting of the Society-for-Medicinal-Plant-and-Natural-Product-Research Basel, Switzerland, Planta Medica International Open; Ausgabe S 01, 2017 https://doi.org/10.1055/s-0037-1608329
• Kirchinger M., Urmann C., Bieler L., Couillard-Despres S., Riepl H. B-Ring Modification in Prenylflavonoids of Hops and the effect on indution of neuronal differentiation. Planta Medica 2016; 82(S 01): S1-S381; DOI: https://doi.org/10.1055/s-0036-1596764
• Luescher S., Urmann C., Riepl H., Butterweck V. Effects of hops Derived Prenylflavonoids on TNF-α Induced Barrier Dysfunction in Intestinal Epithelial Cells. Planta Medica 2016; 82(S 01): S1-S381; https://doi.org/10.1055/s-0036-1596115
• Urmann C., Kirchinger M., Bieler L., Couillard-Despres S., Aigner L., Riepl H. Strucural Modification of Xanthohumol C and the Effect on Inducing differentiation in neural precursor cells. Planta Medica 2015; 81 – SL5C-05; https://doi.org/10.1055/s-0035-1565357
• Urmann C., Oberbauer E., Aigner L., Riepl H. Prenylflavonoids from hops induce neural differentiation independent from an estrogen-like activity Planta Med 2014; 80 – P2O13 https://doi.org/10.1055/s-0034-1395007
• Urmann, C., Oberbauer, E., Aigner, L., Riepl, H. New approach to large scale isolation of rare prenylflavonoids; Planta Medica 2013; 79 PJ49; https://doi.org/10.1055/s-0033-1352253
• Urmann C.; Oberbauer E.: Aigner L.; Riepl H. Neurogenesis-inducing flavonoids: A structure-activity study; Planta Medica 2013, 79 SL 50; https://doi.org/10.1055/s-0033-1351876
• Urmann C., Oberbauer E., Aigner L. and Riepl H.: Differentiation Effects of Prenylflavanones and Chalcones Present in Hops in Neuronal Tissue Cultures; Planta Medica, 2011, 77 – SL52; https://doi.org/10.1055/s-0031-1282175

Contributions to scientific events (not published)

• Ritter S., Urmann C., Riepl H.: Extraction, Anti-oxidative Capacity and Cytotoxicity of Baccosides, 19th International Congress of the International Society for Ethnopharmacology (ISE2019): Dresden, Germany
• Vogl M., Bieler L., Roustan V., Urmann C., Riepl H., Aigner L., Weckwerth W., Couillard-Després S.: ENDF1 neutralises extracellular matrix associated inhibitor effect on DRG neurons outgrowth; 10th FENS Forum of Neuroscience; Kopenhagen. 2016.
• Vogl M., Bieler L., Roustan V., Urmann C., Riepl H., Aigner L., Weckwerth W., Couillard-Després S.: Morphological and proteomic responses of neuronal cells to ENDF1; Neurogenesis; Bordeaux. 2016.
• Vogl M., Bieler L., Roustan V., Urmann C., Riepl H., Aigner L., Weckwerth W., Couillard-Després S.: Morphological and proteomic responses of neuronal cells to ENDF1; PMU Science Get Together; Salzburg. 2016.
• Bieler L., Vogl M., Garnweidner L., Urmann C., Riepl H., Aigner L. and Couillard-Després S.; Beta – Cyclodextrins as nanocarriers for neuroregenerative flavonoids; SCITReCS-Summit; Salzburg. 2015.
• Vogl M., Bieler L., Garnweidner-Raith L., Urmann C., Riepl H., Aigner L., Weckwerth W., Couillard-Després S.: ENDF1: A proregenerative flavonoid for spinal cord injury; Paracelsus Science Get Together; Nürnberg. 2015.
• Vogl M., Bieler L., Urmann C., Riepl H., Aigner L., Weckwerth W., Couillard-Després S.: ENDF1 and its pro-regenerative effects on postnatal DRG neurons; SCI-TReCS Summit; Salzburg. 2015.
• Vogl M., Bieler L., Urmann C., Riepl H., Aigner L., Weckwerth W., Couillard-Després S.: ENDF1 and its pro-regenerative effects on postnatal DRG neurons; ANA annual meeting; Salzburg. 2015.